neurological disorder

The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis

ABSTRACT The therapeutic potential of cannabidiol (CBD), the major nonpsychoactive component of cannabis, was explored in murine collagen-induced arthritis (CIA). CIA was elicited by immunizing DBA/1 mice with type II collagen (CII) in complete Freund’s adjuvant. The CII used was either bovine or murine, resulting in classical acute CIA or in chronic relapsing CIA, respectively. …

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Managing drug-resistant epilepsy: challenges and solutions

ABSTRACT To date, there are restricted data assessing chronic models of epilepsy as well as animal models of epileptogenesis. Some clinical evidence indicates that CBD is able to manage epilepsy in adults and children affected by refractory seizures, with a favorable side effect profile. Tzadok et al treated 74 pediatric patients, who were resistant to …

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