neurological disorder

Endocannabinoid system in systemic lupus erythematosus: First evidence for a deranged 2-arachidonoylglycerol metabolism.

ABSTRACT The endocannabinoid (eCB) system plays a key role in many physiological and pathological conditions and its dysregulation has been described in several rheumatological and autoimmune diseases. Yet, its possible alteration in systemic lupus erythematosus (SLE) has never been investigated. Here, we aimed filling this gap in plasma and peripheral blood mononuclear cells (PBMCs) of …

Endocannabinoid system in systemic lupus erythematosus: First evidence for a deranged 2-arachidonoylglycerol metabolism. Read More »

Sep 28 2019

CBD Oil for Lupus: Is it Safe? Effective? Legal?

ABSTRACT With a lack of research on CBD oil for lupus, we have to go on what we know about CBD in general and what we can understand from research into conditions with similar symptoms or pathology. This potential treatment is likely to get attention from lupus researchers eventually, though, for several reasons.Lupus contributes to …

CBD Oil for Lupus: Is it Safe? Effective? Legal? Read More »

Aug 28 2019

Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis

ABSTRACT These studies demonstrate transdermal administration of CBD has long-lasting therapeutic effects without psychoactive side-effects. Thus, use of topical CBD has potential as effective treatment of arthritic symptomatology. At present, one in five (21%) adults worldwide are diagnosed with some form of arthritis by their physicians (Helmick et al., 2008). The data presented suggest transdermal …

Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis Read More »

Aug 26 2019

Transdermal cannabidiol reduces inflammation and pain‐related behaviours in a rat model of arthritis

ABSTRACT Measurement of plasma CBD concentration provided by transdermal absorption revealed linearity with 0.6–6.2 mg/day doses. Transdermal CBD gel significantly reduced joint swelling, limb posture scores as a rating of spontaneous pain, immune cell infiltration and thickening of the synovial membrane in a dose‐dependent manner. PWL recovered to near baseline level. Immunohistochemical analysis of spinal …

Transdermal cannabidiol reduces inflammation and pain‐related behaviours in a rat model of arthritis Read More »

Aug 26 2019

Endocannabinoid system in systemic lupus erythematosus: First evidence for a deranged 2-arachidonoylglycerol metabolism.

CBD Oil for Lupus: Is it Safe? Effective? Legal?

Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis

Transdermal cannabidiol reduces inflammation and pain‐related behaviours in a rat model of arthritis

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These statements have not been evaluated by the FDA. This product is not intended diagnose, treat, cure or prevent disease.