acne

Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System

ABSTRACT This concept was further supported by a small, single-blind, split-face study, in which a cream containing 3% Cannabis seed extract was applied twice daily to the cheeks of patients for 12 weeks. The treatment was found to be efficient in reducing sebum production and erythema compared to the vehicle treated side [124]. Moreover, a …

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Sep 28 2019

Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes

ABSTRACT We additionally found that CBD also prevented the “pro-acne” LA-T combination from elevating the expression of TNFA (Figure 3A), a key cytokine in the pathogenesis of acne vulgaris (2, 24–30). These data suggested that CBD may exert antiinflammatory actions on human sebocytes (as had already been demonstrated for CBD in several other experimental models, …

Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes Read More »

Aug 28 2019

Differential effectiveness of selected non-psychotropic phytocannabinoids on human sebocyte functions implicates their introduction in dry/seborrhoeic skin and acne treatment.

ABSTRACT Moreover, THCV suppressed proliferation, and all phytocannabinoids exerted remarkable anti-inflammatory actions. Our data suggest that CBG and CBGV may have potential in the treatment of dry-skin syndrome, whereas CBC, CBDV and especially THCV show promise to become highly efficient, novel anti-acne agents. Moreover, based on their remarkable anti-inflammatory actions, phytocannabinoids could be efficient, yet …

Differential effectiveness of selected non-psychotropic phytocannabinoids on human sebocyte functions implicates their introduction in dry/seborrhoeic skin and acne treatment. Read More »

Jul 28 2019

A therapeutic effect of cbd-enriched ointment in inflammatory skin diseases and cutaneous scars

ABSTRACT Based on skin evaluations (hydration, TEWL, elasticity), clinical questionnaires (SCORAD, ADI, PASI), and supported by photographic data and investigators’ clinical assessment, the results showed that topical treatment with CBD-enriched ointment significantly improved the skin parameters, the symptoms and also the PASI index score. No irritant or allergic reactions were documented during the period treatment. …

A therapeutic effect of cbd-enriched ointment in inflammatory skin diseases and cutaneous scars Read More »

May 28 2019

Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System

Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes

Differential effectiveness of selected non-psychotropic phytocannabinoids on human sebocyte functions implicates their introduction in dry/seborrhoeic skin and acne treatment.

A therapeutic effect of cbd-enriched ointment in inflammatory skin diseases and cutaneous scars

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These statements have not been evaluated by the FDA. This product is not intended diagnose, treat, cure or prevent disease.