Cannabinoids in attention-deficit/hyperactivity disorder: A randomised-controlled trial.
Abstract Adults with ADHD describe self-medicating with cannabis, with some reporting a preference for cannabis over ADHD medications. A small number of psychiatrists in the US prescribe cannabis medication for ADHD, despite there being no evidence from randomised controlled studies. The
A prospective open‐label trial of a CBD/THC cannabis oil in dravet syndrome
PURPOSE The purpose of this study was to establish a dose guideline for pure CBD therapy for seizure reduction. The mean dose of CBD achieved was 13.3 mg/kg/day of CBD (range 7–16 mg/kg/day). Based on the dose measurements below, this would be approximately
Cannabidiol: A New Hope for Patients With Dravet or Lennox-Gastaut Syndromes
ABSTRACT Pure, plant-based CBD is a pharmaceutical grade extract that exhibits clinically significant antiseizure properties, with a hypothesized multimodal mechanism of action. In the GWPCARE trial series, CBD displayed superior efficacy in reducing key seizure frequencies (convulsive seizures in DS; drop
Long-term cannabidiol treatment in patients with Dravet syndrome: An open-label extension trial
ABSTRACT By November 2016, a total of 278 patients had completed the original randomized trials, and 264 (95%) enrolled in this open-label extension. Median treatment duration was 274 days (range 1-512) with a mean modal dose of 21 mg/kg/d, and patients
