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The Therapeutic Potential of Cannabis and Cannabinoids

ABSTRACT Cannabis-based medications exert their effects mainly through the activation of cannabinoid receptors (CB1 and CB2). More than 100 controlled clinical trials of cannabinoids or whole-plant preparations for various indications have been conducted since 1975. The findings of these trials have led to the approval of cannabis-based medicines (dronabinol, nabilone, and a cannabis extract [THC:CBD=1:1]) …

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HIV & AIDS: Cannabinoids and CBD Research Overview

ABSTRACT While the side effects of HIV and AIDS treatments can impinge on one’s life quality, studies have shown that medical cannabis can help make the adverse effects more manageable. HIV positive patients consuming medical Cannabis have reported significant improvements in appetite, muscle pain levels, nausea, anxiety, depression, and skin tingling. Studies have found that …

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Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis.

ABSTRACT CBD targets enteric reactive gliosis, counteracts the inflammatory environment induced by LPS in mice and in human colonic cultures derived from UC patients. These actions lead to a reduction of intestinal damage mediated by PPARgamma receptor pathway. Our results therefore indicate that CBD indeed unravels a new therapeutic strategy to treat inflammatory bowel diseases. …

Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis. Read More »

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