dravet syndrome

Epilepsy and Cannabis: A Literature Review

ABSTRACT Epilepsy is considered to be one of the most common non-communicable neurological diseases especially in low to middle-income countries. Approximately one-third of patients with epilepsy have seizures that are resistant to antiepileptic medications. Clinical trials for the treatment of medically refractory epilepsy have mostly focused on new drug treatments, and result in a significant …

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Could Cannabidiol be a Treatment Option for Intractable Childhood and Adolescent Epilepsy?

ABSTRACT Some U.S. states now allow the use of cannabis for medical treatment. Many patients with epilepsy have wanted to try cannabis as a treatment even though preclinical and clinical evidence is limited. As mentioned above, several clinical studies have investigated CBD after the late 19th century. Recent studies have shown an effect of CBD …

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A prospective open‐label trial of a CBD/THC cannabis oil in dravet syndrome

PURPOSE The purpose of this study was to establish a dose guideline for pure CBD therapy for seizure reduction. The mean dose of CBD achieved was 13.3 mg/kg/day of CBD (range 7–16 mg/kg/day). Based on the dose measurements below, this would be approximately 1 full dropper of CBD oil from the 500mg bottle of CBD oil. Initial research in …

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