cbd for childhood illness

Managing drug-resistant epilepsy: challenges and solutions

ABSTRACT To date, there are restricted data assessing chronic models of epilepsy as well as animal models of epileptogenesis. Some clinical evidence indicates that CBD is able to manage epilepsy in adults and children affected by refractory seizures, with a favorable side effect profile. Tzadok et al treated 74 pediatric patients, who were resistant to …

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Could Cannabidiol be a Treatment Option for Intractable Childhood and Adolescent Epilepsy?

ABSTRACT Some U.S. states now allow the use of cannabis for medical treatment. Many patients with epilepsy have wanted to try cannabis as a treatment even though preclinical and clinical evidence is limited. As mentioned above, several clinical studies have investigated CBD after the late 19th century. Recent studies have shown an effect of CBD …

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Long-term cannabidiol treatment in patients with Dravet syndrome: An open-label extension trial

ABSTRACT By November 2016, a total of 278 patients had completed the original randomized trials, and 264 (95%) enrolled in this open-label extension. Median treatment duration was 274 days (range 1-512) with a mean modal dose of 21 mg/kg/d, and patients received a median of 3 concomitant antiepileptic medications. Adverse events (AEs) occurred in 93.2% …

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Cannabidiol Oil Safely Lessens Seizures in Treatment-resistant Children, Early Trial Data Show

ABSTRACT A team led by researchers at University of Saskatchewan, Canada, are conducting an open-label Phase 1 clinical study (NCT03024827) called CARE-E. Scientists are exploring the safety and impact of increasing doses of CBD-enriched cannabis herbal extract (CHE) used as add-on therapy in up 28 children (ages 1 to 10) with epileptic encephalopathy resistant to …

Cannabidiol Oil Safely Lessens Seizures in Treatment-resistant Children, Early Trial Data Show Read More »

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